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The elimination was biphasic, with half-lives of 18—21 min and 8. The 14 C exercise was quickly distributed in main tissues similar to muscle tissue, kidneys, and liver, with out indication of bioaccumulation Merker et al. Any new info being provided in the course of the OECD assessment shall be provided to the IPCS so that an addendum may be prepared for consideration.

In both species, there were no opposed effects on last imply body weights, haematology, or clinical chemistry parameters, and no chemical-associated gross or microscopic lesions had been observed. In Cavo R6UT4H24 U/UTP Cat.6 4x2xAWG24/1 – non schermato – guaina LSZH Euroclasse Dca – QUBIX examine, rats have been uncovered to zero or zero. No thyroid hormone measurements have been carried out.

More usual-use situations would lead to exposures of about 0. Further particulars weren't given.

  • In a research in a plant producing resorcinol by sulfonation of benzene — and likewise producing beta -resorcylic acid, resorcinol—formaldehyde resins, sulfites, and sulfates — staff had been exposed primarily to resorcinol, but the exposure to other brokers was not measured for publicity levels, see section 6.

  • Resorcinol caused no opposed effects in several replica and developmental toxicity studies in rats and rabbits.

  • In controls and the high-dose group, a qualitative histopathological evaluation of the brain forebrain, midbrain, and hindbrain was also carried out for the aforementioned animals RTF, There had been no opposed results regarding reproductive performance, mortality, and physique or organ weights.

  • However, taking into La mia casa è stata venduta all’asta. Quando dovrò lasciare il mio motionless? for toxicity to aquatic crops, the NOEC for algae may be assumed to be larger than that for Daphnia magna.

  • JECFA assessed the hazards from using resorcinol as a food flavouring agent and concluded that this use is of no security concern.

  • Mostly unfavorable results were reported within the initiation—promotion research carried out utilizing a number of species.

  • In one other study, rats have been exposed to zero or 0.

Thyroid glands from all surviving F 0 parents were examined microscopically, and mind measurements have been carried out on all uncovered F 1 pups and those F 1 pups selected for behavioural testing. There were no vital intercourse variations. In , a greater proportion was excreted as sulfate conjugate, whereas males excreted a better proportion of a diconjugate both sulfate and glucuronide groups. From these information, the authors concluded that male rats have a better capability for glucuronidation than females.
From the scarce data out there, the use of resorcinol in hair dyes zero. The use of anti-acne cream is taken because the state of affairs of most concern due to the probability of steady exposure.

For the benthic and terrestrial compartments, the obtainable toxicity data cannot be considered sufficient for a quantitative threat characterization. However, these compartments are less related for resorcinol, due to marginal releases and emissions to these compartments in addition to a very low potential for adsorption of resorcinol to organic matter.

The bulk of the urine-recovered dye should have been taken up into the sexy layer of the skin and then slowly launched into the circulation. A cumulative four-day absorption assuming cm 2 of scalp was given as 0.